• Autoimmune disease and risk of postpartum venous thromboembolism 

      Walker, Rob F.; Zakai, Neil A.; Mason, Susan M.; MacLehose, Richard F.; Norby, Faye L.; Evensen, Line Holtet; Alonso, Alvaro; Lutsey, Pamela L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-23)
      Background - The risk of pregnancy-related mortality in the United States has nearly doubled since 1990, with venous thromboembolism (VTE) accounting for approximately 10% of these deaths.<p> <p>Objectives - The objective of this study was to assess whether preexisting autoimmune disease is a risk factor for postpartum VTE.<p> <p>Methods - Using the MarketScan Commercial and Medicare Supplemental ...
    • Behandling av prostatakreft uten spredning: hurtigoversikt for samvalgsverktøy (oppdatering) 

      Klem, Hanna Eikås; Evensen, Line Holtet (Research report; Forskningsrapport, 2023)
      Prostatakreft er den nest hyppigst diagnostiserte kreftsykdommen blant menn over hele verden. Selv om forekomsten av prostatakreft er høy, er dødeligheten relativt lav. Begrepet lokalt begrenset prostatakreft spenner fra pasienter med lav risiko som ikke skal behandles, til høy risiko som skal behandles. Vi inkluderte en systematisk oversikt om effekten av kirurgi sammenlignet med aktiv overvåkning ...
    • Cardiorespiratory fitness and future risk of venous thromboembolism 

      Evensen, Line Holtet; Isaksen, Trond; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-25)
      <i>Background</i> - Cardiorespiratory fitness (CRF) is a strong predictor of future arterial cardiovascular disease and premature mortality. However, there are limited data on the association between CRF and the risk of incident venous thromboembolism (VTE).<p><p> <i>Objectives</i> - To investigate whether estimated CRF (eCRF) was associated with the risk of incident VTE in a cohort recruited ...
    • Complement factors B, D, C3bBbP and risk of future venous thromboembolism 

      Skjeflo, Espen Waage; Evensen, Line Holtet; Jensen, Søren Beck; Latysheva, Nadezhda; Michelsen, Annika Elisabet; Ueland, Thor; Brækkan, Sigrid Kufaas; Hindberg, Kristian Dalsbø; Snir, Omri; Mollnes, Tom Eirik; Hansen, John Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-07)
      The complement system appears to be involved in the pathogenesis of venous thromboembolism (VTE).<p> <p>We investigated the association of complement factors (CF) B, D, and the alternative pathway convertase, C3bBbP, measured at inclusion, with the risk of future VTE in a nested case-control study; 380 VTE patients and 804 age- and sex-matched controls derived from the Tromsø study. Odds ratios ...
    • Dietary intake of marine n-3 polyunsaturated fatty acids and future risk of venous thromboembolism 

      Isaksen, Trond; Evensen, Line Holtet; Johnsen, Stein Harald; Jacobsen, Bjarne K.; Hindberg, Kristian; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-13)
      <p><i>Background</i>: Studies on the association between long‐chained n‐3 polyunsaturated fatty acids (n‐3 PUFAs) and risk of venous thromboembolism (VTE) are conflicting, potentially due to challenges related to assessment of n‐3 PUFA intake and changes in diet during follow‐up.</p> <p><i>Objectives</i>: To investigate whether dietary intake of marine n‐3 PUFAs was associated with risk of incident ...
    • Dietary Intake of Marine Polyunsaturated n-3 Fatty Acids and Risk of Recurrent Venous Thromboembolism 

      Isaksen, Trond; Evensen, Line Holtet; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-28)
      <i>Background</i> - Limited knowledge exists on the association between intake of long-chained n-3 polyunsaturated fatty acids (n-3 PUFAs) and risk of recurrence and all-cause mortality in patients with venous thromboembolism (VTE).<p><p> <i>Objectives</i> - This article investigates whether intake of marine n-3 PUFAs was associated with risk of recurrence and mortality in patients with incident ...
    • Hemostatic factors, inflammatory markers, and risk of incident venous thromboembolism: The Multi-Ethnic Study of Atherosclerosis 

      Evensen, Line Holtet; Folsom, Aaron R.; Pankow, James S.; Hansen, John-Bjarne; Allison, Matthew; Cushman, Mary; Lutsey, Pamela L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-27)
      Background - Several hemostatic factors and inflammatory markers are associated with the risk of incident venous thromboembolism (VTE), however, most existing data are from case-control studies in Caucasian populations.<p> <p>Objectives - We aimed to prospectively confirm previous findings and explore less studied biomarkers in relation to VTE risk in a multi-racial/multi-ethnic cohort.<p> <p>Methods ...
    • Hysterektomi ved kraftige menstruasjonsblødninger: forenklet metodevurdering 

      Evensen, Line Holtet; Espeland, Anna Lien; Ashtiani, Vida Hamidi; Risstad, Hilde; Elvsaas, Ida-Kristin Ørjasæter (Research report; Forskningsrapport, 2021-06-10)
      Vi har på oppdrag fra Bestillerforum for nye metoder utarbeidet en forenklet metodevurdering om hysterektomi (kirurgisk fjerning av livmor) ved kraftige menstruasjonsblødninger. Dette er en pilot i et prosjekt innen revurdering som ledes av Helse Midt-Norge RHF. Vi har hentet ut resultater for effekt og sikkerhet og vurderinger av tillit til resultatene for effekt fra en rapport av The National ...
    • Impact of prothrombotic genotypes on the association between family history of myocardial infarction and venous thromboembolism 

      Småbrekke, Birgit; Balteskard Rinde, Ludvig; Evensen, Line Holtet; Morelli, Vania Maris; Hveem, Kristian; Gabrielsen, Maiken Elvestad; Njølstad, Inger; Mathiesen, Ellisiv B.; Rosendaal, Frits Richard; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-24)
      <i>Background</i>: Family history of myocardial infarction (FHMI) is known to increase the risk of venous thromboembolism (VTE).<p> <p><i>Objectives</i>: To investigate the effect of prothrombotic genotypes on the association between FHMI and VTE in a case‐cohort recruited from a general population.<p> <p><i>Methods</i>: Cases with a first VTE (<i>n</i> = 1493) and a subcohort (<i>n</i> = ...
    • Nasjonale og regionale melde- og varselordninger for uønskede hendelser i pasientbehandlingen: systematisk oversikt 

      Evensen, Line Holtet; Lidal, Ingeborg Beate; Hafstad, Elisabet Vivianne; Ames, Heather Melanie R (Research report; Forskningsrapport, 2022)
      Alle virksomheter som yter helse- og omsorgstjenester skal arbeide systematisk for å redusere risiko for pasientskade som følge av tjenesteytelsen eller mangel på ytelse. Likevel oppstår uønskede hendelser av varierende alvorlighetsgrad. Anslagsvis rammer uønskede hendelser én av ti pasienter i norske sykehus. Norske virksomheter som yter helse- og omsorgstjenester plikter å varsle om alvorlige ...
    • Physical activity and risk of recurrence and mortality after incident venous thromboembolism 

      Evensen, Line Holtet; Isaksen, Trond; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-15)
      <i>Background</i> - Limited data exist on the relationship between physical activity and major complications after incident venous thromboembolism (VTE).<p> <p><i>Objectives</i> - To investigate whether physical activity was associated with risk of recurrence and mortality in patients with VTE recruited from the general population.<p> <p><i>Methods</i> - Patients with incident VTE (n = 786) ...
    • Physical activity, cardiorespiratory fitness and venous thromboembolism 

      Evensen, Line Holtet (Doctoral thesis; Doktorgradsavhandling, 2020-02-07)
      Venous thromboembolism (VTE) is a serious disease that represents a growing public health concern, and identification of modifiable risk factors is a priority. Although physical activity and cardiorespiratory fitness (CRF) are associated with a wealth of health benefits, their associations with VTE remain to be established. The aim of the present thesis was to summarize knowledge and to identify ...
    • Regular physical activity and risk of venous thromboembolism 

      Evensen, Line Holtet; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-05)
      Venous thromboembolism (VTE) is a complex multifactorial disease that represents a growing public health concern. Identification of modifiable risk factors at the population level may provide a measure to reduce the burden of VTE. In this review, we summarize current knowledge of the role of physical activity on the risk of VTE and VTE-related complications. We also discuss methodological challenges ...
    • Repeated assessments of physical activity and risk of incident venous thromboembolism 

      Evensen, Line Holtet; Isaksen, Trond; Hindberg, Kristian; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-06)
      <p><i>Background</i>: Whether physical activity influences the risk of incident venous thromboembolism (VTE) remains controversial, potentially because of methodological challenges, such as regression dilution bias.</p> <p><i>Objectives</i>: To investigate whether physical activity was associated with VTE risk, and explore the role of body mass index (BMI) as a mediator in a population‐based ...
    • Sutur av degenerative rotatorcuff-rupturer: en fullstendig metodevurdering 

      Evensen, Line Holtet; Kleven, Linn; Dahm, Kristin Thuve; Hafstad, Elisabet Vivianne; Holte, Hilde H; Robberstad, Bjarne; Risstad, Hilde (Research report; Forskningsrapport, 2023)
      Vi har utarbeidet en fullstendig metodevurdering av kirurgi med sutur sammenlignet med ikke-kirurgisk behandling ved degenerativ fulltykkelse rotatorcuff-ruptur. Vi inkluderte fem randomiserte og 18 ikke-randomiserte studier. Vi sammenstilte studiene i metaanalyser og vurderte tilliten til effektestimatene med GRADE-tilnærmingen. <p> <uli> <li>For pasienter med ruptur i én sene gir kirurgi liten ...
    • Utvalgt forskning om melde- og varselordninger i helse- og omsorgstje-nesten: forenklet metodevurdering – kartlegging 

      Evensen, Line Holtet; Lidal, Ingeborg Beate; Hafstad, Elisabet Vivianne; Ames, Heather Melanie R (Research report; Forskningsrapport, 2022-10)
      En nylig utført systematisk oversikt viste at det ikke finnes forskning som har undersøkt effekten av nasjonale og regionale, generelle melde- og varselordninger på alvorlige hendelser i helse- og omsorgstjenesten. Derfor var det hensiktsmessig å undersøke forskning som har sett på tilgrensende problemstillinger.<p> <p>Formålet med dette arbeidet var å kartlegge studier om mulige sammenhenger ...